Mitigating bisphenol A-induced apoptosis in KGN cells: the therapeutic role of 1,25-dihydroxyvitamin D < sub > 3 < /sub > through upregulation of PGC-1 α expression and inhibition of the mitochondrial cytochrome c pathway

CONCLUSIONS: 1,25(OH)2VD3 mitigated BPA-induced damage and apoptosis in KGN cells by upregulating the expression of PGC-1α and impeding the mitochondrial cytochrome c (Cyt c) apoptotic pathway. This study established a novel theoretical foundation for utilizing vitamin D in the treatment of PCOS patients.PMID:38421590 | DOI:10.1007/s42000-024-00539-w
Source: Hormones - Category: Endocrinology Authors: Source Type: research