Perinatal risk factors associated with acute kidney injury severity and duration among infants born extremely preterm

CONCLUSION: We identified major risk factors for severe AKI that can be the focus of future research.IMPACT STATEMENT: Time-dependent risk factors for severe acute kidney injury (AKI) and its duration are not well defined among infants born <28 weeks' gestation. Over 1 in 5 infants born <28 weeks' gestation experienced severe AKI, and this study identified several major time-dependent perinatal risk factors occurring within 72 h prior to severe AKI. This study can support efforts to develop risk stratification and clinical decision support to help mitigate modifiable risk factors to reduce severe AKI occurrence and duration.PMID:38438550 | DOI:10.1038/s41390-024-03102-w

Source: Pediatric Research - March 4, 2024 Category: Pediatrics Authors: Keia Sanderson Russell Griffin Nekayla Anderson Andrew M South Jonathan R Swanson Michael Zappitelli Heidi J Steflik Marissa J DeFreitas Jennifer Charlton David Askenazi Neonatal Kidney Collaborative (NKC) Research Committee Source Type: research