Integrated data from intravital imaging and HPLC-MS/MS analysis reveal large interspecies differences in AFB < sub > 1 < /sub > metabolism in mice and rats

In conclusion, major differences between mice and rats were observed, concerning the nuclear persistence, formation of AFB1-lysine adducts, and the AFB1-guanine adducts.PMID:38436695 | DOI:10.1007/s00204-024-03688-4

Source: Archives of Toxicology - March 4, 2024 Category: Toxicology Authors: Reham Hassan Andrea Gerdemann Benedikt Cramer Zaynab Hobloss Maiju Myllys Daniela Gonz ález Wiebke Albrecht Jannik Veerkamp Adrian Friebel Stefan Hoehme Melanie Esselen Gisela H Degen Hans-Ulrich Humpf Jan G Hengstler Ahmed Ghallab Source Type: research