Activation of free fatty acid receptors, FFAR1 and FFAR4, ameliorates ulcerative colitis by promote fatty acid metabolism and mediate macrophage polarization

CONCLUSION: Activated FFAR1 and FFAR4 ameliorates DSS-induced UC by promoting fatty acid metabolism to reduce lipid accumulation and mediate M2 macrophage polarization.PMID:38432147 | DOI:10.1016/j.intimp.2024.111778

Source: International Immunopharmacology - March 3, 2024 Category: Allergy & Immunology Authors: Lin-Sheng Zhang Zhi-Shou Zhang Yu-Zhu Wu Botang Guo Jing Li Xiao-Qi Huang Feng-Min Zhang Min-Yao Li Ping-Chang Yang Xue-Bao Zheng Source Type: research