A simple and accurate ratiometric sensor for determination of dopamine based on dual-emission carbon dots

In this study, an economic and accurate DA ratiometric sensor was established using dual-emission carbon dots (DE-CDs). DE-CDs were first synthesized by the one-step solvothermal method and two separate fluorescence emission peaks at 340 and 500 nm were observed under the excitation of 310 nm. In the presence of Hg2+, the fluorescence signal at 340 nm was significantly quenched, while the signal at 500 nm keeps stable. Upon adding DA, the quenched signal at 340 nm was significantly recovered, whereas the signal at 500 nm remains stable. Therefore, a novel ratiometric sensor for DA analysis was established. This method shows a good linear range from 500 nM to 100 μM, and the detection limit was calculated to be 80 nM. Moreover, this established method shows excellent specificity and could be applied in real sample analysis, showing great potential for application in clinical research.PMID:38430366 | DOI:10.1007/s44211-023-00492-5

Source: Anal Sci - March 2, 2024 Category: Chemistry Authors: Yuecheng Zhang Lingbo Sun Chengjia Li Jing Ma Shiyu Zhang QingQing Wang Hongyan Ma Source Type: research