Autophagy markers are decreased in bone of osteoporotic patients: a monocentric comparative study

CONCLUSIONS: These results demonstrate for the first time that postmenopausal OP patients have a deficit in bone autophagy level and suggest that HUNK could be the factor linking estrogen loss and autophagy decline.CLINICAL TRIAL REGISTRATION NUMBER: ClinicalTrials.gov Identifier: NCT03175874, 2/6/2017.PMID:38430550 | DOI:10.1093/ejendo/lvae017

Source: European Journal of Endocrinology - March 2, 2024 Category: Endocrinology Authors: Marie-Charlotte Trojani Arnaud Clav é Isabelle Bereder Olivier Camuzard R égis Bernard De Dompsure Jean-Fran çois Gonzalez Christophe Trojani Sabine Santucci-Darmanin Georges F Carle V éronique Breuil Val érie Pierrefite-Carle Source Type: research