Achieving an optimal pregnancy outcome through the combined utilization of micro-TESE and ICSI in cryptorchidism associated with a non-canonical splicing variant in RXFP2

ConclusionThis is the first cryptorchidism case carrying a novel causative non-canonical splicingRXFP2 variant. The combined approach of micro-TESE and ICSI contributed to an optimal pregnancy outcome. Our literature review demonstrated thatRXFP2 variants caused cryptorchidism in a recessive inheritance pattern, rather than a dominant pattern.

http://link.springer.com/10.1007/s10815-024-03070-4

Source: Journal of Assisted Reproduction and Genetics - March 2, 2024 Category: Reproduction Medicine Source Type: research