Successful treatment of simultaneous malignant pleural mesothelioma and pulmonary adenocarcinoma: A case report

Oncol Lett. 2024 Feb 15;27(4):155. doi: 10.3892/ol.2024.14288. eCollection 2024 Apr.ABSTRACTThe present report described the case of a 74-year-old male patient with asbestos exposure whose chest computed tomography revealed a right lower lobe nodule and right pleural effusion. Pleural biopsy led to the diagnosis of epithelial malignant pleural mesothelioma (cT2N0M0, stage IB). Combination therapy with cisplatin + pemetrexed led to the complete remission of malignant pleural mesothelioma; however, the right lower lobe nodule grew in size over time. The patient was subsequently diagnosed with lung adenocarcinoma (cT1aN0M0, stage IA1) by computed tomography-guided biopsy performed 18 months after chemotherapy initiation and achieved remission of lung adenocarcinoma with stereotactic radiotherapy. The patient was alive without recurrence at the 12-month follow-up. The present case illustrated that multiple active regimens are currently available for malignant pleural mesothelioma and lung cancer that can aid in the treatment of complex cases.PMID:38426158 | PMC:PMC10902755 | DOI:10.3892/ol.2024.14288
Source: Oncology Letters - Category: Cancer & Oncology Authors: Source Type: research