Including the liver in the visceral allograft: Impact on donor-specific anti-HLA antibodies and long-term outcomes

In conclusion, liver-containing visceral allografts have superior short- and long-term outcomes compared with liver-free allografts. De novo DSA develop early and frequently after VTx performed without B cell-depleting induction therapy, but the exact role of DSA in the pathogenesis of rejection remains unclear.PMID:38418315 | DOI:10.1016/j.humimm.2024.110767

Source: Human Immunology - February 28, 2024 Category: Allergy & Immunology Authors: Dace Abele Markus G äbel Mihai Oltean Jonas Varkey Johan M ölne Nils Ekwall Helena Borg Hanna Jacobsson Jan Holgersson Gustaf Herlenius Source Type: research