BCL6 attenuates hyperoxia-induced lung injury by inhibiting NLRP3-mediated inflammation in fetal mouse

CONCLUSIONS: BCL6 inhibits NLRP3-mediated inflammation, attenuates alveolar simplification and dysregulated pulmonary vessel development in hyperoxia-induced BPD mice. Hence, BCL6 may be a target in treating BPD and neonatal diseases.PMID:38419581 | DOI:10.1080/01902148.2024.2320665

Source: Experimental Lung Research - February 29, 2024 Category: Respiratory Medicine Authors: Dan Chen Hui-Min Zhao Xian-Hui Deng Sheng-Peng Li Mei-Hui Zhou Ya-Xian Wu Ying Tong Ren-Qiang Yu Qing-Feng Pang Source Type: research