Evidence that inositol 1,4,5-trisphosphate 3-kinase and inositol 1,3,4,5-tetrakisphosphate are negative regulators of platelet function

CONCLUSION: ITPK and IP4 are negative regulators of platelet function. IP4 regulation of PH domain-containing proteins may represent a pathway by which platelet activation may be controlled during thrombosis.PMID:38404940 | PMC:PMC10885593 | DOI:10.1016/j.rpth.2024.102326

Source: Thrombosis and Haemostasis - February 26, 2024 Category: Hematology Authors: Kalwant S Authi Sabeeya Khan Jonathan M Gibbins Susan D Brain Source Type: research