Splicing targeting drugs highlight intron retention as an actionable vulnerability in advanced prostate cancer

CONCLUSIONS: Our study uncovers intron retention as an actionable vulnerability for advanced PC, which may be exploited to improve therapeutic management of this currently incurable disease.PMID:38413979 | PMC:PMC10898177 | DOI:10.1186/s13046-024-02986-0

Source: Clinical Prostate Cancer - February 27, 2024 Category: Cancer & Oncology Authors: Chiara Naro Ambra Antonioni Vanessa Medici Cinzia Caggiano Ariane Jolly Pierre de la Grange Pamela Bielli Maria Paola Paronetto Claudio Sette Source Type: research