Medium-intensity statin with ezetimibe versus high-intensity statin in acute ischemic cerebrovascular disease (MESIA):a randomized clinical trial

Compared to guideline-recommended high-intensity statin therapy, moderate-intensity statin with ezetimibe further improved the achievement rate of LDL-C in patients with acute ischemic cerebrovascular disease, with a higher reduction magnitude in LDL-C. In terms of safety, there was no significant difference between the two regimens, suggesting that moderate-intensity statin with ezetimibe can also be considered as an initial treatment option for patients with acute ischemic cerebrovascular disease.

Source: Journal of Stroke and Cerebrovascular Diseases - February 28, 2024 Category: Neurology Authors: Xuxian Lv, Xudong Liu, Yanfang Peng, Wenbin Li, Jianing Wang, Xiaofeng Chen, Junjie Lei, Chaogang Tang, Shijian Luo, Weihua Mai, Yiming Cai, Qian Fan, Liu Chenhao, Lei Zhang Source Type: research