Functional brain connectivity in children with focal epilepsy: A systematic review of functional MRI studies

Focal epilepsy is the predominant type of epilepsy in children [1] and adults [2]. Patients with focal epilepsy have seizures arising from an epileptogenic zone or local network, but we now also understand focal epilepsy as a disorder affecting the connectivity of wider brain networks [3 –6]. Growing evidence suggests that focal epilepsy is associated with widespread brain connectivity alterations, which may be pathophysiological underpinnings of seizure generation and propagation [7,8]. Brain connectivity describes the structural and functional interactions between discrete brain regions.
Source: Seizure: European Journal of Epilepsy - Category: Neurology Authors: Source Type: research