Determination of Factors Associated with Upstage in Atypical Ductal Hyperplasia to Identify Low-Risk Patients Where Active Surveillance May be an Alternative

CONCLUSIONS: The upstage rate among 221 ADH lesions was 16.7%, highest in lesions ≥ 10 mm, with pathologic suspicion of DCIS, and linear/regional calcifications on mammography. Conversely, 30% of the cohort exhibited all low-risk factors, with an upstage rate < 2%, suggesting that active surveillance may be permissible in lieu of surgery.PMID:38386195 | DOI:10.1245/s10434-024-15041-1

Source: Ann Oncol - February 22, 2024 Category: Cancer & Oncology Authors: Alexandra J E Greene Joshua Davis Jessica Moon Iram Dubin Anastasia Cruz Megha Gupta Ashkan Moazzez Junko Ozao-Choy Esha Gupta Tejas Manchandia Babak N Kalantari Guita Rahbar Christine Dauphine Source Type: research