Accumulation of circulating myeloid-derived suppressor cell subsets: predicting poor clinical efficacy and prognosis through T cell suppression in non-Hodgkin's lymphoma

In conclusion, our study demonstrates that the increased circulating MDSC subsets predict poor clinical efficacy and prognosis in NHL, potentially involving T cell suppression through MDSC subsets expansion. These findings indicate the potential of MDSC subsets as comprehensive diagnostic, prognostic biomarkers, and therapeutic targets for NHL.PMID:38369808 | DOI:10.1093/jleuko/qiae032

Source: Journal of Leukocyte Biology - February 19, 2024 Category: Hematology Authors: Lian-Fang Pu Man-Man Li Xiang-Jiang Feng Tun Zhang Lin-Hui Hu Hui-Min Zheng Alice Charwudzi Yang-Yang Ding Jun Liu Ze-Lin Liu Shu-Dao Xiong Source Type: research