Association of reduced cerebrospinal fluid NPTX2 levels with postoperative delirium in patients undergoing knee/hip replacement: a prospective cohort study

CONCLUSION: CSF NPTX2 levels were associated with the occurrence of POD. Low CSF NPTX2 levels may be an independent protective factor for POD. CSF T-tau and P-tau could mediate the association between CSF NPTX2 and POD occurrence.CLINICAL TRIAL REGISTRATION: The trial registration number (TRN): ChiCTR2200064740, Date of Registration: 2022-10-15.PMID:38367123 | PMC:PMC10874313 | DOI:10.1007/s40520-023-02670-x
Source: Aging Clinical and Experimental Research - Category: Geriatrics Authors: Source Type: research