Clustering the cortical laminae: in vivo parcellation

This study aims to offer a robust, whole-brain validation of T1 imaging as a practical and effective tool for exploring the laminar composition of the cortex. To do so, we cluster complex microstructural cortical datasets of both human (N = 30) and macaque (N = 1) brains using an adaptation of an algorithm for clustering cell omics profiles. The resulting cluster patterns are then compared to established atlases of cytoarchitectonic features, exhibiting significant correspondence in both species. Lastly, we demonstrate the expanded applicability of T 1 imaging by exploring some of the cytoarchitectonic features behind various unique skillsets, such as musicality and athleticism.

Source: Anatomy and Embryology - January 9, 2024 Category: Anatomy Source Type: research