Inhibition of Alzheimer's disease by 4-octyl itaconate revealed by RNA-seq transcriptome analysis

CONCLUSIONS: Overall, the results of this study demonstrated that 4-OI improved cognitive deficits in AD mice, confirming the therapeutic effect of 4-OI on AD.PMID:38369275 | DOI:10.1016/j.ejphar.2024.176432

Source: European Journal of Pharmacology - February 18, 2024 Category: Drugs & Pharmacology Authors: Yingchao Liu Pengcheng Xia Shuai Zong Ni Zheng Xiaolin Cui Cuicui Wang Miaomiao Wang Xueying Wang Shuyi Yu Hao Zhao Zhiming Lu Source Type: research