2% chlorhexidine gluconate aqueous versus 2% chlorhexidine gluconate in 70% isopropyl alcohol for skin disinfection prior to percutaneous central venous catheterisation: the ARCTIC randomised controlled feasibility trial

Conclusions A definitive comparative efficacy trial is feasible, but the very low catheter colonisation rate would make a large-scale RCT challenging due to the very large sample size required. ARCTIC provides preliminary reassurance supporting potential safe use of 2% CHG-70% IPA and 2% CHG-aqueous in preterm neonates. Trial registration number ISRCTN82571474.

http://fn.bmj.com/cgi/content/short/109/2/202?rss=1

Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - February 19, 2024 Category: Perinatology & Neonatology Authors: Clarke, P., Soe, A., Nichols, A., Harizaj, H., Webber, M. A., Linsell, L., Bell, J. L., Tremlett, C., Muthukumar, P., Pattnayak, S., Partlett, C., King, A., Juszczak, E., Heath, P. T. Tags: Open access Original research Source Type: research