Rethinking the clinical research protocol: Lessons learned from the COVID-19 pandemic and recommendations for reducing noncompliance

CONCLUSION: These noncompliance events have implications for clinical trial methodology because nonadherence to trial design can lead to participant safety concerns and loss of trial data validity. Protocols should be written to better facilitate the capture of all safety and efficacy data. This recommendation should be considered when changes occur to the protocol environment that are outside of the study team's control.PMID:38366865 | DOI:10.1177/17407745241232430

Source: Clinical Trials - February 17, 2024 Category: Research Authors: Matthew J Gooden Gina Norato Katherine Landry Sandra B Martin Avindra Nath Lauren Reoma Source Type: research