Cumulative methotrexate dose is not associated with liver fibrosis in patients with a history of moderate to severe psoriasis

CONCLUSION: This study confirms a high prevalence of significant LF in patients with psoriasis. Cumulative methotrexate dose was not associated with LF. Patients with BMI ≥28 kg/m2, metabolic syndrome and diabetes are at higher risk for LF. These risk factor may help to identify when a more detailed liver health assessment is needed.PMID:38366967 | DOI:10.1093/bjd/ljae069

Source: The British Journal of Dermatology - February 17, 2024 Category: Dermatology Authors: Parastoo Babakinejad Rebecca Lapsley Lara Forster Stuart McPherson Mark S Pearce Nick J Reynolds Emma Slack Sophie C Weatherhead Philip J Hampton Source Type: research