Nerve ultrasound in Friedreich's Ataxia: enlarged nerves as a biomarker of disease severity

CONCLUSIONS: Our study shows that high-resolution ultrasound reveals notable nerve abnormalities, primarily in the upper limbs of patients diagnosed with Friedreich's Ataxia. The observed correlation between these nerve abnormalities and clinical disability scales indicates the potential use of this technique as a biomarker for evaluating disease severity and treatment effects.SIGNIFICANCE: Nerve Ultrasound is a potential biomarker of disease severity in Friedreich's Ataxia.PMID:38359552 | DOI:10.1016/j.clinph.2024.01.004

Source: Clinical Neurophysiology - February 15, 2024 Category: Neurology Authors: G Di Pietro E Cioffi P Falco E Galosi G De Stefano G Di Stefano C Leone V Martines S Perotti C Casali A Truini Source Type: research