Genetically engineered mouse model of pleomorphic liposarcoma: Immunophenotyping and histologic characterization

CONCLUSION: Genetically engineered RPP mice reliably produced soft-tissue tumors consistent with pleomorphic liposarcoma, which immunological findings similar to other soft-tissue sarcomas. This model may demonstrate utility in testing treatments for this rare disease, including immunomodulatory therapies.PMID:38199172 | PMC:PMC10788790 | DOI:10.1016/j.neo.2023.100956

Source: Neoplasia - January 10, 2024 Category: Cancer & Oncology Authors: Jeffrey Mark Brown Rahi Patel Kyllie Smith-Fry Michael Ward Trudy Oliver Kevin B Jones Source Type: research