Unveiling Liquid Gold: Lymph as an HPV Marker in OPSCC to guide treatment decisions

Clin Cancer Res. 2024 Jan 22. doi: 10.1158/1078-0432.CCR-23-3549. Online ahead of print.ABSTRACTDistinguishing low versus high-risk HPV-associated oropharyngeal squamous cell carcinoma (OPSCC) is pivotal for tailoring treatment. Liquid biopsy, measuring cell-free HPV-DNA in serum and saliva, assesses treatment response and early-recurrence risk. Postoperative lymphatic fluid, may better guide future adjuvant therapy decisions due to its proximity to primary lesions and lymph nodes.PMID:38252056 | DOI:10.1158/1078-0432.CCR-23-3549

Source: Clinical Cancer Research - January 22, 2024 Category: Cancer & Oncology Authors: Nicholas Brian Shannon N Gopalakrishna Iyer Source Type: research