Reviving: restoring depression-like behaviour through glial cell-derived neurotrophic factor treatment in the medial prefrontal cortex

CONCLUSION: Our findings support a positive effect of exogenous GDNF on synaptic plasticity, mediated by DRD1 signalling in the mPFC, which could facilitate depression remission in Parkinson disease.PMID:38302136 | PMC:PMC10843345 | DOI:10.1503/jpn.230079

Source: J Psychiatry Neurosc... - February 1, 2024 Category: Psychiatry Authors: Yehao Liu Xiaoyu Zhou Ke Xue Ruiao Sun Yan Tang Chuanxi Tang Source Type: research