Efficacy and Safety of Iloperidone in Bipolar Mania: A Double-Blind, Placebo-Controlled Study

Conclusions: Iloperidone is effective in treating patients with bipolar mania. The tolerability and safety profile of iloperidone in bipolar mania is consistent with previous clinical studies of patients with schizophrenia, and no new safety concerns were identified.Trial Registration: ClinicalTrials.gov identifier: NCT04819776; EudraCT: 2020-000405-83.PMID:38236020 | DOI:10.4088/JCP.23m14966

Source: Journal of Clinical Psychiatry - January 18, 2024 Category: Psychiatry Authors: Rosarelis Torres Emily L Czeisler Sean R Chadwick Stephen M Stahl Sandra P Smieszek Changfu Xiao Christos M Polymeropoulos Gunther Birznieks Mihael H Polymeropoulos Source Type: research