Jun/Fos promotes migration and invasion of hepatocellular carcinoma cells by enhancing BORIS promoter activity

In conclusion, these results suggest that Jun and Fos can promote the development of hepatocellular carcinoma by directly regulating the expression of BORIS. These findings may provide experimental evidence positioning BORIS as a novel target for the clinical intervention of hepatocellular carcinoma.PMID:38281696 | DOI:10.1016/j.biocel.2024.106540

Source: The International Journal of Biochemistry and Cell Biology - January 28, 2024 Category: Biochemistry Authors: Longjun Xian Yimei Xiong Lu Qin Ling Wei Siqi Zhou Qinda Wang Qiang Fu Mingmei Chen Yang Qin Source Type: research