Niacin increases human aortic endothelial Sirt1 activity and nitric oxide: effect on endothelial function and vascular aging

CONCLUSIONS: Translationally, these findings suggest that Sirt1 activation by niacin may be one of the mechanisms of action of niacin acting on NO to improve endothelial function and mitigate human vascular aging and its deleterious cardiovascular consequences.PMID:38186996 | PMC:PMC10767546
Source: American Journal of Translational Research - Category: Research Authors: Source Type: research