Academy of Orthopaedic Surgeons Technology Overview Summary: Concentrated Bone Marrow Aspirate for Knee Osteoarthritis

J Am Acad Orthop Surg. 2024 Jan 30. doi: 10.5435/JAAOS-D-23-00957. Online ahead of print.ABSTRACTThe Platelet-Rich Plasma (PRP) for Knee Osteoarthritis Technology Overview is based on a systematic review of current scientific and clinical research. Through analysis of the current best evidence, this technology overview seeks to evaluate the efficacy of PRP for patients with knee osteoarthritis. The systematic literature review resulted in 54 articles: 36 high-quality and 18 moderate-quality. The findings of these studies were summarized to present findings on PRP versus control/placebo, acetaminophen, non-steroidal anti-inflammatory drugs, corticosteroids, exercise, prolotherapy, autologous conditioned serum, bone marrow aspirate concentrate, hyaluronic acid, and ozone therapy. In addition, the work group highlighted areas that needed additional research when evidence proved lacking on the topic and carefully noted the potential harms associated with an intervention, required resource utilization, acceptability, and feasibility.PMID:38295392 | DOI:10.5435/JAAOS-D-23-00957

Source: The Journal of the American Academy of Orthopaedic Surgeons - January 31, 2024 Category: Orthopaedics Authors: Jonathan Dubin Philipp Leucht Martha Murray Ryan Pezold Staff of the American Academy of Orthopaedic Surgeons Source Type: research