Cephaeline promotes ferroptosis by targeting NRF2 to exert anti-lung cancer efficacy

CONCLUSION: We demonstrated for the first time that cephaeline inhibits NRF2, leading to ferroptosis in lung cancer cells. These findings may contribute to the development of innovative therapeutics for lung cancer.PMID:38339810 | PMC:PMC10860416 | DOI:10.1080/13880209.2024.2309891

Source: Pharmaceutical Biology - February 10, 2024 Category: Drugs & Pharmacology Authors: Peng Chen Qingxuan Ye Shang Liang Linghui Zeng Source Type: research