Kidney resident macrophages have distinct subsets and multifunctional roles

CONCLUSIONS: We identified CD81 and CX3CR1 positive kidney macrophage subsets with distinct dependence for monocyte replenishment. Multiomic analysis demonstrated that these cells have diverse functions that underscore the importance of macrophages in kidney health and disease.PMID:38331051 | DOI:10.1016/j.matbio.2024.02.002

Source: Matrix Biology - February 8, 2024 Category: Molecular Biology Authors: Christine Chew Oliver J Brand Tomohiko Yamamura Craig Lawless Mychel Raony Paiva Teixeira Morais Leo Zeef I-Hsuan Lin Gareth Howell Sylvia Lui Franziska Lausecker Christopher Jagger Tovah N Shaw Siddharth Krishnan Flora A McClure Hayley Bridgeman Kelly We Source Type: research