Cardiac functional adaptation to resistance and endurance exercise training: A randomised cross-over study

This study investigated changes in left ventricular (LV) systolic and diastolic function following endurance (END) and resistance (RES) training in healthy participants. 64 individuals participated in a randomized cross-over design trial, involving 12-weeks of END and RES training, separated by a 12-week washout. Echocardiograms assessed systolic function (ejection fraction (EF), and global longitudinal strain (GLS)), diastolic function (mitral valve early velocity (E), tissue Doppler velocity (e'), their ratio (E/e')), and left atrial volume indexed to body surface area (LA ESVi). LV mass (LVM) increased with both RES (Δ 5.3±11.9, P=0.001) and END (Δ 7.5±13.9, P<0.001). Once adjusted for lean body mass (LVMi), changes remained significant following END. E/e' improved following END (Δ -0.35±0.98, P=0.011) not RES (Δ 0.35±1.11, P=0.157; P=0.001 between modes). LA ESVi increased with END (Δ 2.0±6.1, P= 0.019) but not RES (Δ 1.7±5.7, P=0.113). EF and GLS were not impacted significantly by either mode of training. Adaptation in LVM and LA volumes, as well as diastolic function were exercise mode specific. Twelve weeks of intensive END increased LVM, LA volumes and increased diastolic function. Following RES, LVM increased, although this was attenuated after accounting for changes in lean body mass. There were no changes in systolic function following either mode of exercise training.PMID:38334974 | DOI:10.1152/ajpheart.00579.2023
Source: American Journal of Physiology. Heart and Circulatory Physiology - Category: Physiology Authors: Source Type: research