Methyl β-Cyclodextrin-sperm-mediated gene editing (MBCD-SMGE): a simple and efficient method for targeted mutant mouse production

CONCLUSION: Overall, this study highlights the significant potential of the MBCD-SMGE technique for generating targeted mutant mice. It holds enormous promise for modeling human diseases and improving desirable traits in animals.PMID:38279106 | PMC:PMC10811837 | DOI:10.1186/s12575-024-00230-9
Source: Biological Procedures Online - Category: Molecular Biology Authors: Source Type: research