Characterization of the Burkholderia mallei tonB Mutant and Its Potential as a Backbone Strain for Vaccine Development

Conclusions/Significance Although further work is needed to prevent chronic infection by TMM001 while maintaining immunogenicity, our attenuated strain demonstrates great potential as a backbone strain for future vaccine development against both glanders and melioidosis.

Source: PLoS Neglected Tropical Diseases - June 26, 2015 Category: Tropical Medicine Authors: Tiffany M. Mott et al. Source Type: research