Ursodeoxycholic acid and 18 β-glycyrrhetinic acid alleviate ethinylestradiol-induced cholestasis via downregulating RORγt and CXCR3 signaling pathway in iNKT cells

In conclusion, our observations provide new therapeutic targets of UDCA and 18β-GA, and 18β-GA as an alternative treatment for EE-induced cholestasis.PMID:38244730 | DOI:10.1016/j.tiv.2024.105782

Source: Toxicology in Vitro - January 20, 2024 Category: Toxicology Authors: Xinyu Li Xiaojing Liang Xiaoxia Gu Mengzhi Zou Weiping Cao Chunhui Liu Xinzhi Wang Source Type: research