Differences in physiological endotypes between non-positional and positional obstructive sleep apnea: Results from Shanghai Sleep Health Study cohort

This study highlights the differences in endotypes between NPOSA and POSA. In Chinese individuals, anatomical factors were more significant in determining the severity of NPOSA, while non-anatomical traits were more likely to determine the severity of POSA. Future research should focus on developing personalized management strategies for individuals with NPOSA and POSA based on their endotypes.CLINICAL TRIAL REGISTRATION NUMBER: The study was approved by the Ethics Committee of Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine (Approval No: 2019-KY-050[K]) and registered at the Chinese Clinical Trial Registry (No. ChiCTR1900025714).PMID:38218217 | DOI:10.1016/j.chest.2024.01.021

Source: Chest - January 13, 2024 Category: Respiratory Medicine Authors: Xiaoting Wang Tianjiao Zhou Weijun Huang Jingyu Zhang Jianyin Zou Jian Guan Hongliang Yi Shankai Yin Source Type: research