Autopsy of a 45-year-old Man with Liver Failure Due to Polycystic Liver Disease

Intern Med. 2024 Feb 1. doi: 10.2169/internalmedicine.2485-23. Online ahead of print.ABSTRACTA 37-year-old man with autosomal polycystic kidney disease (ADPKD) was admitted to our hospital with a liver volume of 8,000 cm3. Hepatic arterial embolization was performed using a microcoil but was ineffective. Eight years later, the hepatomegaly progressed to liver failure and death. At autopsy, the liver weighed 21.5 kg, and the entire liver had been replaced by cysts; in the few remaining areas of liver parenchyma, microscopic, small cysts of various sizes and fibrosis were evident, with only a few normal hepatocytes observed. Hepatic arterial branches developed; however, the portal vein could not be observed.PMID:38296484 | DOI:10.2169/internalmedicine.2485-23

Source: Internal Medicine - January 31, 2024 Category: Internal Medicine Authors: Masato Mizuta Akinari Sekine Tatsuya Suwabe Junichi Hoshino Masayuki Yamanouchi Hiroki Mizuno Daisuke Ikuma Eiko Hasegawa Yuki Oba Kei Kono Keiichi Kinowaki Kenichi Ohashi Naoki Sawa Yoshifumi Ubara Source Type: research