Gastric Burkitt's monomorphic post-transplant lymphoproliferative disorder after kidney transplantation: A case report

We report on a 53-year-old Japanese man diagnosed with gastric Burkitt's monomorphic post-transplant lymphoproliferative disorder (B-PTLD) after endoscopy for gastric discomfort 28 months after the patient underwent renal transplantation in Ethiopia. Serum Epstein-Barr virus (EBV) tests were negative before transplantation, but the tumor cells collected from a gastric biopsy showed positive EBV-encoded small RNAs (EBER) at B-PTLD onset. Intensive treatment started with R(rituximab)-CHOP therapy and continued with DA-EPOCH-R therapy has been effective, and relapse has not yet occurred. Burkitt lymphoma has a poor prognosis, but B-PTLD may be effectively treated with high-dose chemotherapy. This is a rare case of gastric B-PTLD in a Japanese patient.PMID:38329919 | DOI:10.5414/CN111321

Source: Clinical Nephrology - February 8, 2024 Category: Urology & Nephrology Authors: Yusuke Yoshimura Tatsuya Suwabe Arisa Fujiki Daisuke Kaji Yuki Asano-Mori Yuki Oba Hiroki Mizuno Masayuki Yamanouchi Kiho Tanaka Eiko Hasegawa Katsuyuki Miki Takayoshi Yokoyama Yuki Namamura Yasuo Ishii Satoshi Yamashita Kei Kono Keiichi Kinowaki Yutaka T Source Type: research