Intratumor genetic heterogeneity and head and neck cancer relapse

CONCLUSION: Intratumor genetic heterogeneity at the level of the cancer driver mutations might explain the discordant mutational profiles in LRs after CRT, while there are no indications in xenograft models that these changes are induced by CRT.PMID:38185257 | DOI:10.1016/j.radonc.2024.110087

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - January 7, 2024 Category: Radiology Authors: A S Pierik J B Poell A Brink M Stigter-van Walsum R H de Roest T Poli A Yaromin P Lambin C R Leemans R H Brakenhoff Source Type: research