MRI analysis of neurodevelopmental anatomy in myelomeningocele: prenatal vs postnatal repair

CONCLUSIONS: We report baseline variations in developmental neuroanatomy in patients with MMC including rates of CC dysgenesis, gray matter heterotopia and additional cranial and spinal MRI findings. We found that prenatal surgery results in changes to infratentorial anatomy, with minimal effect on supratentorial brain development. This information will be useful in myelomeningocele counseling and in understanding how prenatal repair of myelomeningocele affects brain development. This article is protected by copyright. All rights reserved.PMID:38237046 | DOI:10.1002/uog.27586

Source: The Ultrasound Review of Obstetrics and Gynecology - January 18, 2024 Category: Radiology Authors: A K Bruzek G M Koller S Karuparti K Varagur A Dunbar T M Flanders M Mingo K Sudanagunta K H Bligard A Odibo J Vrecenak A Mian J M Strahle Source Type: research