Topological alteration of the brain structural network in Parkinson's disease with apathy

CONCLUSIONS: The findings suggested that apathy in PD presented relatively optimized global topological properties of the brain structural network and disrupted topological organization of the regional network, particularly involving the fronto-striatal-limbic circuits. The altered topological properties of abnormal brain regions might be used to understand the physiopathologic mechanism of the neural network in aPD patients.PMID:38340778 | DOI:10.1016/j.brainresbull.2024.110899

Source: Brain Research Bulletin - February 10, 2024 Category: Neurology Authors: Shaoyun Ge Jun Liu Yongfeng Jia Zihan Li Jianwei Wang Min Wang Source Type: research