Phenytoin enzyme induction for management of supratherapeutic tacrolimus levels due to drug-drug interaction with nirmatrelvir/ritonavir: Case series and discussion

CONCLUSION: These observations demonstrate that metabolism induction using phenytoin may be a useful strategy in the setting of supratherapeutic tacrolimus levels resulting from concomitant administration with nirmatrelvir/ritonavir.PMID:38347740 | DOI:10.1093/ajhp/zxae032

Source: American Journal of Health-System Pharmacy : AJHP - February 13, 2024 Category: Drugs & Pharmacology Authors: Jennifer Marsh Angela T Logan Erin P Bilgili Lyndsey J Bowman Allyssa R Webb Source Type: research