Update on Asthma Biology

This is an exciting time to be conducting asthma research. The recent development of targeted asthma biologics has validated the power of basic research to discover new molecules amenable to therapeutic intervention. Advances in high throughput sequencing are providing a wealth of “-omic” data about genetic and epigenetic underpinnings of asthma, as well as new cellular interacting networks and potential endotypes in asthma. Airway epithelial cells have emerged not only as key sensors of the outside environment, but also as central drivers of dysregulated mucosal immune r esponses in asthma.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Source Type: research