Post Transplant Bendamustine Partially Replacing Cyclophosphamide As Gvhd Prophylaxis in T Cell Replete Haploidentical Stem Cell Transplantation-Single Center Experience

Post –transplant cyclopshophamide (PTCy) is the commonly applied graft-versus-host disease (GVHD) prophylaxis regimen in T cell replete haplo-stem cell transplantation. Although PT-CY attained great success in HaploSCT arena to prevent GVHD but complicated with higher incidence of Veno-occlusive diseas e (VOD) and infections. To mitigate these we have attempted a different approach, replacing the Day+4 PTCy with Bendamustine (PT-BEN).

Source: Biology of Blood and Marrow Transplantation - February 1, 2024 Category: Hematology Authors: Joydeep Chakrabartty, Arijit Bishnu, Akash Bhojgaria, Mihir Das, Sara Panmei, Ranjith Kumar CS, Amrita Chakravarti Tags: 412 Source Type: research