Effects of CYP3A4*22 and POR*28 variations on the pharmacokinetics of tacrolimus in renal transplant recipients: a meta-analysis of 18 observational studies

This study aimed to investigate the association between cytochrome P450 (CYP) 3A4*22 and cytochrome P450 oxidoreductase (POR)*28 variations and the pharmacokinetics of tacrolimus.

Source: BMC Nephrology - February 6, 2024 Category: Urology & Nephrology Authors: Ze Li, Xiaozhen Wang, Dandan Li, Sheng Cheng, Zhe Li, Heng Guo, Yiwen Dong, Yingming Zheng and Xingang Li Tags: Research Source Type: research