Vitamin D is Not a Protective Factor in ALS.
Vitamin D is Not a Protective Factor in ALS. CNS Neurosci Ther. 2015 Jun 20; Authors: Blasco H, Madji Hounoum B, Dufour-Rainfray D, Patin F, Maillot F, Beltran S, Gordon PH, Andres CR, Corcia P Abstract AIMS: Vitamin D deficiency has been associated with poorer prognosis in ALS. Better understanding of the role of vitamin D in ALS is needed to determine whether trials of systematic supplementation are justified. Our aim was to report vitamin D levels during the course of ALS and to evaluate its relationship with clinical parameters at diagnosis and with disease progression. METHODS: We prospectively collected vitamin D serum concentrations from 125 consecutive ALS patients. Cox proportional hazard models analyzed the relationship between vitamin D concentrations, clinical parameters, and survival. RESULTS: The mean vitamin D concentration was below our laboratory's lower limit of normal (P
Conclusion: This study confirmed the association of vitamin D deficiency with hypothyroidism, thyroid autoimmunity, increased volume, nodularity, and vascularity of thyroid gland in hypothyroid patients as well as increased HOMA-IR. It proved the association between HOMA-IR and thyroid autoimmunity. The study proved no association between VDR polymorphisms (Fok1 and Apa1) with either vitamin D levels or TSH levels. PMID: 31534663 [PubMed]
Conclusion: Appropriate vitamin D levels were shown to be important in preventing the onset of CRC. PMID: 31534963 [PubMed - in process]
Vitamin D deficiency has been strongly linked to increased mortality and is especially associated with diabetes-related deaths in younger people, according to new research presented at the European Society for Paediatric Endocrinology’s annual meeting in Vienna, Austria.Medical Xpress
(Natural News) Rickets is a skeletal disorder caused by a deficiency of calcium, phosphate, and vitamin D — nutrients needed for the formation of healthy bones. As a result, children who suffer from rickets tend to have weak bones, abnormal growth, and problems with their skeletal structure. Recently, a rise in the number of rickets cases,...
Conclusion: A significant proportion of this large cohort of south Indian healthy rural postmenopausal women had osteoporosis at either site with advancing age. Most of them had a suboptimal DCI, and over half of them had VDD.
Publication date: Available online 18 September 2019Source: The Journal of Steroid Biochemistry and Molecular BiologyAuthor(s): Rolf Jorde, Tom Wilsgaard, Guri GrimnesAbstractVitamin D deficiency is associated with diabetes, cancer, immunological and cardiovascular diseases as well as increased mortality. It has, however, been difficult to show a causal relation in randomized, controlled trials. Mendelian randomization studies provide another option for testing causality, and results indicate relations between the serum 25-hydroxyvitamin D (25(OH)D) level and some diseases, including mortality. We have from the Troms&oslas...
Publication date: Available online 18 September 2019Source: The Journal of Steroid Biochemistry and Molecular BiologyAuthor(s): Francesca L Crowe, Rasiah Thayakaran, Neil Gittoes, Martin Hewison, G Neil Thomas, Robert Scragg, Krishnarajah NirantharakumarAbstractBackgroundThere is increasing evidence that vitamin D supplementation may only be beneficial in people with vitamin D deficiency, and the lack of sufficient people with very low vitamin D levels could explain the lack of protection against cardiovascular disease (CVD) reported in recent clinical trials of vitamin D supplementation. The aim of this study was to asses...
In conclusion, using these levels of addition, at least one food vehicle was able to increase per capita vitamin D supply to ≥5 μg/d in each of the LMICs.
Exposing skin to sunlight is a convenient way to meet our vitamin D needs, which is crucial for bone health. That might make you wonder: Does wearing sunscreen interfere with vitamin D levels and potentially cause vitamin D deficiency?