PET-CT-guided versus CT-guided biopsy in suspected malignant pleural thickening: a randomised trial
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Pleural malignancy represents either metastases from another primary site (often lung, breast or ovarian) or primary pleural malignancy from pleural mesothelioma [1]. Pleural malignancy, especially pleural mesothelioma, can be challenging to diagnose due to the patchy distribution of heterogenous tumour across the pleural surface [2]. Pleural biopsy via image guidance or thoracoscopy has a false negative rate of 10–25% [3, 4]. For those with a non-diagnostic first pleural biopsy, but ongoing clinical or radiological suspicion of malignancy, the optimal approach is unclear.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: de Fonseka, D., Arnold, D. T., Smartt, H. J. M., Culliford, L., Stadon, L., Tucker, E., Morley, A., Zahan-Evans, N., Bibby, A. C., Lynch, G., Mishra, E., Khan, S., Haris, M., Steer, H., Lewis, L., Ionescu, A., Harvey, J., Blyth, K., Rahman, N. M., Edey, A Tags: Lung cancer Original Articles: Imaging and pleural disease Source Type: research
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