High-sensitivity C-reactive protein in heart failure with preserved ejection fraction: Findings from TOPCAT

Inflammation plays a central role in the genesis and progression of heart failure with preserved ejection fraction (HFpEF). C-reactive protein (CRP) is widely used as means to assess systemic inflammation, and elevated levels of CRP have been associated with poor HF prognosis. Identification of chronic low-grade inflammation in outpatients can be performed measuring high-sensitivity CRP (hsCRP). The clinical characteristics and outcome associations of a pro-inflammatory state among outpatients with HFpEF requires further study.

Source: International Journal of Cardiology - January 30, 2024 Category: Cardiology Authors: Jo ão Pedro Ferreira, Brian L. Claggett, Jiankang Liu, Abhinav Sharma, Akshay S. Desai, Inder S. Anand, Eileen O'Meara, Jean L. Rouleau, Simon De Denus, Bertram Pitt, Marc A. Pfeffer, Faiez Zannad, Scott D. Solomon Tags: Short communication Source Type: research