IKK β deletion from CNS macrophages increases neuronal excitability and accelerates the onset of EAE, while from peripheral macrophages reduces disease severity
Multiple sclerosis (MS) is a neuroinflammatory demyelinating disease characterized by motor deficits and cognitive decline. Many immune aspects of the disease are understood through studies in the experimental...
Source: Journal of Neuroinflammation - Category: Neurology Authors: Maria Avloniti, Maria Evangelidou, Maria Gomini, Theodore Loupis, Mary Emmanouil, Adamantia Mitropoulou, Theodore Tselios, Hans Lassmann, Agn ès Gruart, José M. Delgado-García, Lesley Probert and Vasiliki Kyrargyri Tags: Research Source Type: research